H.E.L.P.eR (aka Humanoid Electric Lab Partner Robot): H.E.L.P.eR. is the robot created by Dr. Jonas Venture Sr. on the Cartoon Network show Venture Brothers created in 2003. H.E.L.P.eR. was originally built to watch over Dr. Jonas Venture's son Rusty. However, now that Rusty (aka Dr. Thaddeus S. Venture) is grown up H.E.L.P.eR. now helps Brock Samson with the task of watching over Hank and Dean, Rusty's sons. This is quite a handful.
(Image courtesy of The Venture Bros Wiki)